Anti-Human/Mouse/Rat Phospho-MAP3K11 (Ser674) Polyclonal Antibody

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01889
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human MLK3 around the phosphorylation site of Ser674
Specificity Expressed in a wide variety of normal and neoplastic tissues including fetal lung, liver, heart and kidney, and adult lung, liver, heart, kidney, placenta, skeletal muscle, pancreas and brain.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q16584
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:5000
Formulation
Application WB,ELISA
Other Names 2610017K16Rik,EC 2.7.11.25,M3K11,Map3k11,MEKK11,MGC17114,Mitogen-activated protein kinase kinase kinase 11,Mixed lineage kinase 3,Mixed lineage protein kinase 3,Mlk-3,Mlk3,Protein tyrosine kinase PTK1,PTK1,RHOE,SH3 domain containing proline rich kinase,SPRK,Src-homology 3 domain-containing proline-rich kinase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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