Anti-Human/Mouse/Rat Phospho-FYN (Tyr530) Polyclonal Antibody

Tyrosine-protein kinase implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels, with isoform 2 showing the greater ability to mobilize cytoplasmic calcium in comparison to isoform 1. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Blocks axon outgrowth and attraction induced by NTN1 by phosphorylating its receptor DDC. Phosphorylates RUNX3.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01782
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human Fyn around the phosphorylation site of Tyr530
Specificity Isoform 1 is highly expressed in the brain. Isoform 2 is expressed in cells of hemopoietic lineages, especially T lymphocytes.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P06241
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Formulation
Application WB,IHC-p,ELISA
Other Names C syn protooncogene,Fyn,FYN oncogene related to SRC FGR YES,FYN,OKT3 induced calcium influx regulator,P59 FYN,p59-Fyn,Protein tyrosine kinase fyn,Proto oncogene tyrosine protein kinase fyn,Proto-oncogene c-Fyn,Proto-oncogene Syn,Protooncogene Syn,SLK,Src like kinase,Src yes related novel gene,Src-like kinase,Src/yes related novel,SYN,Tyrosine kinase p59fyn T,Tyrosine kinase p59fyn(T),Tyrosine-protein kinase Fyn
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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