Anti-Human/Mouse/Rat Phospho-EZR (Tyr146) Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA01696
Size	100μl
Host Type	Rabbit
Immunogen	Synthesized peptide derived from human Ezrin around the phosphorylation site of Y146.
Specificity	Expressed in cerebral cortex, basal ganglia, hippocampus, hypophysis, and optic nerve. Weakly expressed in brain stem and diencephalon. Stronger expression was detected in gray matter of frontal lobe compared to white matter (at protein level). Component of the microvilli of intestinal epithelial cells. Preferentially expressed in astrocytes of hippocampus, frontal cortex, thalamus, parahippocampal cortex, amygdala, insula, and corpus callosum. Not detected in neurons in most tissues studied.
Isotype	IgG
Reacitivity	Human,Mouse,Rat
Clone
Uniprot	P15311
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, ELISA 1:40000
Formulation
Application	WB,ELISA
Other Names	Villin 2 ezrin,CVIL,CVL,Cytovillin 2,Cytovillin,DKFZp762H157,Epididymis secretory protein Li 105,EZR,EZRI,Ezrin,FLJ26216,HEL S 105,MGC1584,p81,VIL 2,VIL2,Villin 2 (ezrin),Villin 2,Villin-2,Villin2
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse/Rat Phospho-EZR (Tyr146) Polyclonal Antibody

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