Anti-Human/Mouse/Rat Phospho-EPOR (Tyr426) Polyclonal Antibody

Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
List Price: $398
  • Buy 5 for $378.1 each and save 5%
  • Buy 21 for $358.2 each and save 10%
  • Buy 31 for $338.3 each and save 15%
  • Buy 51 for

Properties

Data Sheet Click for Datasheet
Catalog Number PA01891
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human EpoR around the phosphorylation site of Y426.
Specificity Erythroid cells and erythroid progenitor cells. Isoform EPOR-F is the most abundant form in EPO-dependent erythroleukemia cells and in late-stage erythroid progenitors. Isoform EPOR-S and isoform EPOR-T are the predominant forms in bone marrow. Isoform EPOR-T is the most abundant from in early-stage erythroid progenitor cells.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P19235
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names EPO R,EPO-R,epor,EPOR,Erythropoietin receptor,Erythropoietin receptor precursor,MGC138358
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

© Copyright 2024 TZYBIOTECH. All Rights Reserved. SiteMap