Anti-Human/Mouse/Rat Phospho-DAPK3 (Thr265) Polyclonal Antibody

Serine/threonine kinase which acts as a positive regulator of apoptosis. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. Regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. Involved in the formation of promyelocytic leukemia protein nuclear body (PML-NB), one of many subnuclear domains in the eukaryotic cell nucleus, and which is involved in oncogenesis and viral infection.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01739
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human DAPK3 around the phosphorylation site of Thr265
Specificity Widely expressed. Isoform 1 and isoform 2 are expressed in the bladder smooth muscle.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O43293
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names DAP kinase 3,DAP like kinase,DAP-like kinase,Dapk 3,DAPK3,DAPK3,Death associated kinase 3,Death associated protein kinase 3,Death-associated protein kinase 3,Dlk,EC 2.7.11.1,FLJ36473,MYPT1 kinase,ZIP,ZIP kinase,ZIP kinase isoform,ZIP-kinase,ZIPK,zipper-interacting protein kinase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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