Anti-Human/Mouse/Rat PERK Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA08486
Size	100μl
Host Type	Rabbit
Immunogen	Synthetic peptide of human EIF2AK3
Specificity	Ubiquitous. A high level expression is seen in secretory tissues.
Isotype	IgG
Reacitivity	Human,Mouse,Rat
Clone
Uniprot	Q9NZJ5
Concentration	0.5 mg/mL
Dilution	IHC 1:50-1:200
Formulation
Application	IHC,ELISA
Other Names	DKFZp781H1925,E2AK3,EC 2.7.11.1,Eif2ak3,Eukaryotic translation initiation factor 2 alpha kinase 3,Eukaryotic translation initiation factor 2-alpha kinase 3,Heme regulated EIF2 alpha kinase,HRI,HsPEK,Pancreatic eIF2 alpha kinase,Pancreatic eIF2-alpha kinase,PEK,PRKR like endoplasmic reticulum kinase,PRKR-like endoplasmic reticulum kinase,WRS
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse/Rat PERK Polyclonal Antibody

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