Anti-Human/Mouse/Rat PEA15 Polyclonal Antibody

This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11824
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human PEA15
Specificity Ubiquitously expressed. Most abundant in tissues such as heart, brain, muscle and adipose tissue which utilize glucose as an energy source. Lower expression in glucose-producing tissues. Higher levels of expression are found in tissues from individuals with type 2 diabetes than in controls.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q15121
Concentration 0.1 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names 15 kDa phosphoprotein enriched in astrocytes,Astrocytic phosphoprotein PEA 15,Astrocytic phosphoprotein PEA-15,Astrocytic phosphoprotein PEA15,HMAT 1,HMAT1,Homolog of mouse MAT 1 oncogene,Homolog of mouse MAT1 oncogene,HUMMAT 1H,HUMMAT1H,MAT 1,MAT 1H,MAT1,MAT1H,PEA 15,Pea15,PEA15 protein,PEA15,PED,Phosphoprotein enriched in astrocytes 15,Phosphoprotein enriched in astrocytes 15kD,Phosphoprotein enriched in diabetes
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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