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Anti-Human/Mouse/Rat PDE4B/C/D Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
PDE4B (Phosphodiesterase 4B) is a Protein Coding gene. Diseases associated with PDE4B include Ocular Hypotension and Acrodysostosis. Among its related pathways are GABAergic synapse and Sweet Taste Signaling. GO annotations related to this gene include ion channel binding and cAMP binding. An important paralog of this gene is PDE4D. PDE4C (Phosphodiesterase 4C) is a Protein Coding gene. Diseases associated with PDE4C include Ocular Hypotension. Among its related pathways are GABAergic synapse and Sweet Taste Signaling. GO annotations related to this gene include 3,5-cyclic-nucleotide phosphodiesterase activity and 3,5-cyclic-AMP phosphodiesterase activity. An important paralog of this gene is PDE4D. PDE4D (Phosphodiesterase 4D) is a Protein Coding gene. Diseases associated with PDE4D include Acrodysostosis 2, With Or Without Hormone Resistance and Acrodysostosis With Multiple Hormone Resistance. Among its related pathways are GABAergic synapse and Sweet Taste Signaling. GO annotations related to this gene include enzyme binding and protein domain specific binding. An important paralog of this gene is PDE4B.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05534
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human PDE4B/C/D around the non-phosphorylation site of S133/119/190.
Specificity PDE4B is Expressed in brain, heart, lung and skeletal muscle.PDE4C isExpressed in various tissues but not in cells of the immune system.PDE4D is Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Formulation
Application WB,IHC-p,ELISA
Other Names PDE4B,DPDE4,cAMP-specific 3',5'-cyclic phosphodiesterase 4B,DPDE4,PDE32,PDE4C,DPDE1,cAMP-specific 3',5'-cyclic phosphodiesterase 4C,DPDE1,PDE21,PDE4D,DPDE3,cAMP-specific 3',5'-cyclic phosphodiesterase 4D,DPDE3,PDE43
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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