Anti-Human/Mouse/Rat PCK1 Polyclonal Antibody

This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09313
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human PCK1
Specificity Major sites of expression are liver, kidney and adipocytes.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P35558
Concentration 1.1 mg/mL
Dilution WB 1:500-1:2000
Formulation
Application WB,ELISA
Other Names cytosolic [GTP],GTP,PCK1,PCKGC,PEP carboxykinase,PEPCK-C,PEPCK1,PEPCKC,Phosphoenolpyruvate carboxykinase 1 (soluble),Phosphoenolpyruvate carboxykinase 1,Phosphoenolpyruvate carboxykinase,Phosphoenolpyruvate carboxykinase,cytosolic [GTP],Phosphoenolpyruvate carboxykinase,cytosolic,Phosphoenolpyruvate carboxylase,Phosphopyruvate carboxylase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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