Anti-Human/Mouse/Rat PCK1 Polyclonal Antibody

This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06383
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human PEPCK-C.
Specificity Major sites of expression are liver, kidney and adipocytes.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P35558
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names cytosolic [GTP],GTP,PCK1,PCKGC,PEP carboxykinase,PEPCK-C,PEPCK1,PEPCKC,Phosphoenolpyruvate carboxykinase 1 (soluble),Phosphoenolpyruvate carboxykinase 1,Phosphoenolpyruvate carboxykinase,Phosphoenolpyruvate carboxykinase,cytosolic [GTP],Phosphoenolpyruvate carboxykinase,cytosolic,Phosphoenolpyruvate carboxylase,Phosphopyruvate carboxylase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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