Anti-Human/Mouse/Rat PAK3 Polyclonal Antibody

PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA07319
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human PAK3
Specificity Restricted to the nervous system. Highly expressed in postmitotic neurons of the developing and postnatal cerebral cortex and hippocampus.1 Publication
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O75914
Concentration 0.3 mg/mL
Dilution WB 1:500-2000, ELISA 1:2000-5000
Formulation
Application WB,ELISA
Other Names Beta PAK,bPAK,CDKN1A,hPAK3,Mental retardation X linked 30,MRX30,MRX47,Oligophrenin 3,OPHN3,p21 (CDKN1A) activated kinase 3,p21 activated kinase 3,p21 CDKN1A activated kinase 3,P21 protein (Cdc42/Rac) activated kinase 3,PAK-3,PAK3 p21 protein (Cdc42/Rac)-activated kinase 3,PAK3beta,Pak65alpha,Pak65beta,Serine threonine protein kinase PAK 3,Stk4
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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