Anti-Human/Mouse/Rat p53R2 Polyclonal Antibody

Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05501
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human p53R2.
Specificity Widely expressed at a high level in skeletal muscle and at a weak level in thymus. Expressed in epithelial dysplasias and squamous cell carcinoma.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q7LG56
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:40000
Formulation
Application WB,ELISA
Other Names DKFZp686M05248,MGC102856,MGC42116,MTDPS8A,MTDPS8B,p53 inducible ribonucleotide reductase small subunit 2 homolog,p53 inducible ribonucleotide reductase small subunit 2 like protein,P53 inducible ribonucleotide reductase small subunit 2 short form beta,p53 R2,p53-inducible ribonucleotide reductase small subunit 2-like protein,p53R2,Ribonucleoside diphosphate reductase M2 subunit B,Ribonucleoside-diphosphate reductase subunit M2 B,Ribonucleotide reductase M2 B (TP53 inducible),Ribonucleotide reductase M2 B,Ribonucleotide reductase small subunit like 2 p53 inducible,RIR2B,RRM 2B,RRM2B,TP53 inducible ribonucleotide reductase M2 B,TP53-inducible ribonucleotide reductase M2 B
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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