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Anti-Human/Mouse/Rat P-Selectin Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06518
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human P-Selectin.
Specificity Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P16109
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000-1:10000
Formulation
Application WB,IHC-p,ELISA
Other Names Antigen CD62,CD62,CD62 antigen-like family member P,CD62P,GMP 140,GMP-140,GMP140,GMRP,Granule membrane protein 140,Granulocyte membrane protein,GRMP,LECAM 3,LECAM3,Leukocyte endothelial cell adhesion molecule 3,Leukocyte-endothelial cell adhesion molecule 3,LYAM3,P Selectin,P-selectin,PADGEM,Platelet activation dependent granule-external membrane protein,Platelet alpha granule membrane protein,PSEL,Selectin P (granule membrane protein 140kDa,antigen CD62),SELP
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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