Anti-Human/Mouse/Rat OTUB1 Polyclonal Antibody

The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10178
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human OTUB1
Specificity Isoform 1 is ubiquitous. Isoform 2 is expressed only in lymphoid tissues such as tonsils, lymph nodes and spleen, as well as peripheral blood mononuclear cells.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q96FW1
Concentration 0.3 mg/mL
Dilution WB 1:500-1:2000
Formulation
Application WB,ELISA
Other Names Deubiquitinating enzyme OTUB1,hOTU1,HSPC263,OTB1,OTU domain containing ubiquitin aldehyde binding protein 1,OTU domain,ubiquitin aldehyde binding 1,OTU domain-containing Ubal-binding protein 1,OTU domain-containing ubiquitin aldehyde-binding protein 1,OTU-domain Ubal-binding 1,OTU1,Otub1,OTUB1,Otubain 1,Otubain-1,Ubiquitin specific processing protease OTUB1,Ubiquitin thioesterase OTUB1,ubiquitin-specific protease otubain 1,Ubiquitin-specific-processing protease OTUB1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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