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Anti-Human/Mouse/Rat Oct-3/4 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04494
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from Oct-3/4
Specificity Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q01860
Concentration 1mg/mL
Dilution WB 1:500-2000, ELISA 1:10000-20000
Formulation
Application WB,ELISA
Other Names Octamer binding transcription factor 4,MGC22487,Oct 3,Oct 4,Oct-3,Oct-4,OCT3,Oct4,Octamer binding protein 3,Octamer binding protein 4,Octamer binding transcription factor 3,Octamer-binding protein 3,Octamer-binding protein 4,Octamer-binding transcription factor 3,OTF 3,OTF 4,OTF-3,OTF3,OTF4,PO5F1,POU class 5 homeobox 1,POU domain class 5 transcription factor 1,POU domain transcription factor OCT4,POU domain,class 5,transcription factor 1,POU-type homeodomain-containing DNA-binding protein,POU5F1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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