Anti-Human/Mouse/Rat NEK8 Polyclonal Antibody

This gene encodes a member of the serine/threionine protein kinase family related to NIMA (never in mitosis, gene A) of Aspergillus nidulans. The encoded protein may play a role in cell cycle progression from G2 to M phase. Mutations in the related mouse gene are associated with a disease phenotype that closely parallels the juvenile autosomal recessive form of polycystic kidney disease in humans. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12698
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human NEK8
Specificity Highest expression in thyroid, adrenal gland and skin. Low levels in spleen, colon and uterus. Overexpressed in breast tumors, with highest expression in infiltrating ductal carcinomas and moderate levels in mucinous adenocarcinoma.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q86SG6
Concentration 0.3 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names JCK,NEK 8,NEK12A,NEK8,NEK8,Nephrocystin 9,Never in mitosis A-related kinase 8,NIMA (never in mitosis gene a) related kinase 8,NIMA related kinase 8,NIMA-family kinase NEK8,NIMA-related kinase 12a,Nima-related protein kinase 12a,NimA-related protein kinase 8,NPHP9,Serine/threonine-protein kinase Nek8
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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