Anti-Human/Mouse/Rat NDRG2 Polyclonal Antibody

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10399
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human NDRG2
Specificity Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues; absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level).
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9UN36
Concentration 0.4 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names Antidepressant related protein ADRG123,Cytoplasmic protein Ndr1,DKFZp781G1938,FLJ25522,KIAA1248,N myc downstream regulated gene 2,N myc downstream regulator 2,NDR1 related protein NDR2,NDRG 2,NDRG family member 2,NDRG1 related protein,NDRG2,NDRG2,Protein NDRG2,Protein Syld709613,SYLD,Syld709613 protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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