Anti-Human/Mouse/Rat NBN Polyclonal Antibody

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10901
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human NBN
Specificity Ubiquitous. Expressed at high levels in testis.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O60934
Concentration 0.5 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names AT V1,AT V2,ATV,Cell cycle regulatory protein p95,FLJ10155,MGC87362,Nbn,NBN,NBS 1,NBS,NBS1,Nibrin,Nijmegen breakage syndrome 1 (nibrin),Nijmegen breakage syndrome,Nijmegen breakage syndrome protein 1,p95,p95 protein of the MRE11/RAD50 complex
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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