Anti-Human/Mouse/Rat MUC5AC Polyclonal Antibody

Mucins are high molecular weight glycoproteins with 80% carbohydrates and 20% core protein. Gastric Mucin 5AC antigen is found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in normal colon. Resurgence of gastric mucin during colonic carcinogenesis is suggestive of either re-expression of the peptide core of gastric mucin in the adult colon or due to changes in the glycosylation pattern of mucin, which expose the hidden Mucin 5AC antigen.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01949
Size 100μl
Host Type Rabbit
Immunogen Recombinant Human Mucin-5AC protein
Specificity Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P98088
Concentration 2 mg/mL
Dilution IHC 1:50-1:100
Formulation
Application IHC
Other Names Apomucin,Apomucin Major Airway Glycoprotein,Gastric mucin,LeB,Lewis B blood group antigen,Major Airway Glycoprotein,MUC 5,MUC5,MUC5AC,Mucin 5 subtype AC tracheobronchial,Mucin 5 Subtypes A And C,Mucin 5 subtypes A and C tracheobronchial/gastric,Mucin 5,tracheobronchial/gastric,Mucin 5AC,Mucin 5AC oligomeric mucus/gel forming,Mucin 5AC,oligomeric mucus/gel forming pseudogene,Mucin,TBM,Tracheobronchial Mucin (TBM),Tracheobronchial mucin
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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