Anti-Human/Mouse/Rat MTUS1 Polyclonal Antibody

This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11887
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human MTUS1
Specificity Ubiquitously expressed (at protein level). Highly expressed in brain. Down-regulated in ovarian carcinoma, pancreas carcinoma, colon carcinoma and head and neck squamous cell carcinoma (HNSCC). Isoform 1 is the major isoform in most peripheral tissues. Isoform 2 is abundant in most peripheral tissues. Isoform 3 is the major isoform in brain, female reproductive tissues, thyroid and heart. Within brain it is highly expressed in corpus callosum and pons. Isoform 6 is brain-specific, it is the major isoform in cerebellum and fetal brain.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9ULD2
Concentration 0.2 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names AGTR2-interacting protein,Angiotensin II type 2 receptor interacting protein,AT2 receptor interacting protein,AT2 receptor-binding protein,AT2R binding protein,ATBP,ATIP,ATIP1,DKFZp586D1519,DKFZp686F20243,Erythroid differentiation related,FLJ14295,GK 1,GK1,KIAA1288,Microtubule associated tumor suppressor 1,Mitochondrial tumor suppressor 1,Mitochondrial tumor suppressor gene 1,MP 44,MP44,MTSG 1,MTSG1,MTUS 1,Transcription factor MTSG1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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