Anti-Human/Mouse/Rat/Monkey ZC3HC1 Polyclonal Antibody

This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis.ZC3HC1 (Zinc Finger C3HC-Type Containing 1) is a Protein Coding gene. Among its related pathways are Apoptosis and Autophagy and DNA Damage. GO annotations related to this gene include protein kinase binding.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05287
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human NIPA around the non-phosphorylation site of S354.
Specificity Widely expressed. Highly expressed in heart, skeletal muscle and testis. Expressed in brain, placenta, lung, kidney, liver, pancreas, spleen, thymus, prostate, ovary small intestine and colon. Weakly or not expressed in leukocytes.
Isotype IgG
Reacitivity Human,Mouse,Rat,Monkey
Clone
Uniprot Q86WB0
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IF 1:200-1:1000, ELISA 1:40000
Formulation
Application WB,IF,ELISA
Other Names hNIPA,NIPA,Nuclear interacting partner of ALK,Nuclear interacting partner of anaplastic lymphoma kinase,Nuclear-interacting partner of ALK,Nuclear-interacting partner of anaplastic lymphoma kinase,zc3hc1,Zinc finger C3HC type containing 1,Zinc finger C3HC-type protein 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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