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Anti-Human/Mouse/Rat/Monkey RACGAP1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05681
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human Rac GAP1 around the non-phosphorylation site of Ser387.
Specificity Highly expressed in testis, thymus and placenta. Expressed at lower levels in spleen and peripheral blood lymphocytes. In testis, expression is restricted to germ cells with the highest levels of expression found in spermatocytes. Expression is regulated in a cell cycle-dependent manner and peaks during G2/M phase.
Isotype IgG
Reacitivity Human,Mouse,Rat,Monkey
Clone
Uniprot Q9H0H5
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names CYK4,GAP,Gap1,GTPase activating protein,HsCYK-4,ID GAP,KIAA1478,Male germ cell RacGap,MgcRacGAP,Protein CYK4 homolg,Protein CYK4 homolog,Rac GTPase activating protein 1,Rac GTPase-activating protein 1,RACGAP 1,Racgap1,RGAP1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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