Anti-Human/Mouse/Rat/Monkey Phospho-YAP1 (Ser127) Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Data Sheet	Click for Datasheet
Catalog Number	PA01806
Size	100μl
Host Type	Rabbit
Immunogen	Synthesized peptide derived from human YAP around the phosphorylation site of Ser127
Specificity	Increased expression seen in some liver and prostate cancers. Isoforms lacking the transactivation domain found in striatal neurons of patients with Huntington disease (at protein level).
Isotype	IgG
Reacitivity	Human,Mouse,Rat,Monkey
Clone
Uniprot	P46937
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Formulation
Application	WB,IHC-p,ELISA
Other Names	65 kDa Yes associated protein,65 kDa Yes-associated protein,COB1,YAp 1,YAP 65,YAP,YAP1,YAP1,YAP2,YAP65,yes -associated protein delta,Yes associated protein 1 65kDa,Yes associated protein 1,Yes associated protein 2,yes associated protein beta,YKI,Yorkie homolog
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse/Rat/Monkey Phospho-YAP1 (Ser127) Polyclonal Antibody

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