Anti-Human/Mouse/Rat/Monkey Phospho-SYK (Tyr525) Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

SYK(spleen tyrosine kinase) is a key regulator of signal transduction events,apoptosis and orderly cell cycle progression in B-lineage lymphoid cells. Although SYK has not been linked to a human disease, defective expression of the closely related T-cell tyrosine kinase ZAP-70 has been associated with severe combined immunodeficiency(PMID:11494125). This protein has 2 isoforms produced by alternative splicing.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA01773
Size	100μl
Host Type	Rabbit
Immunogen	Synthesized peptide derived from human Syk around the phosphorylation site of Tyr525
Specificity	Widely expressed in hematopoietic cells (at protein level). Within the B-cells compartment it is for instance expressed for pro-B-cells to plasma cells.
Isotype	IgG
Reacitivity	Human,Mouse,Rat,Monkey
Clone
Uniprot	P43405
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Formulation
Application	WB,IHC-p,ELISA
Other Names	EC 2.7.10.2,kinase Syk,KSYK,KSYK,p72-Syk,p72syk,Spleen tyrosine kinase,Syk,Tyrosine protein kinase SYK,Tyrosine-protein kinase SYK
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse/Rat/Monkey Phospho-SYK (Tyr525) Polyclonal Antibody

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