Anti-Human/Mouse/Rat/Monkey Phospho-CXCR4 (Ser339) Polyclonal Antibody

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01868
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human Fusin around the phosphorylation site of Ser339
Specificity Expressed in numerous tissues, such as peripheral blood leukocytes, spleen, thymus, spinal cord, heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, cerebellum, cerebral cortex and medulla (in microglia as well as in astrocytes), brain microvascular, coronary artery and umbilical cord endothelial cells. Isoform 1 is predominant in all tissues tested.
Isotype IgG
Reacitivity Human,Mouse,Rat,Monkey
Clone
Uniprot P61073
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names C-X-C chemokine receptor type 4,CD184,CD184 antigen,Chemokine (C X C motif) receptor 4,Chemokine CXC Motif Receptor 4,CXC-R4,CXCR-4,CXCR4,CXCR4,D2S201E,FB22,Fusin,HM89,HSY3RR,LAP 3,LAP3,LCR1,LESTR,Leukocyte derived seven transmembrane domain receptor,Leukocyte-derived seven transmembrane domain receptor,Lipopolysaccharide associated protein 3,Neuropeptide Y receptor Y3,NPY3R,NPYR,NPYRL,NPYY3,NPYY3R,Probable G protein coupled receptor lcr1 homolog,SDF 1 receptor,SDF-1 receptor,SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR,Stromal cell derived factor 1 receptor,Stromal cell-derived factor 1 receptor,WHIM,WHIMS
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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