Anti-Human/Mouse/Rat/Monkey Phospho-CRK (Tyr221) Polyclonal Antibody

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01731
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human Crk II around the phosphorylation site of Tyr221
Specificity
Isotype IgG
Reacitivity Human,Mouse,Rat,Monkey
Clone
Uniprot P46108
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:40000
Formulation
Application WB,IF,ELISA
Other Names Adapter molecule crk,Avian sarcoma virus CT10 (v crk) oncogene homolog,CRK,CRK isoform 2,CRK isoform II,CRK,CRKII,FLJ38130,OTTHUMP00000115366,OTTHUMP00000198330,p38,Proto oncogene C crk,Proto-oncogene C-crk,v crk avian sarcoma virus CT10 oncogene homolog,v crk sarcoma virus CT10 oncogene homolog,v crk sarcoma virus CT10 oncogene homolog (avian)
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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