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Anti-Human/Mouse/Rat/Monkey HSD17B10 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03810
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human ERAB
Specificity Expressed in normal tissues but is overexpressed in neurons affected in AD.
Isotype IgG
Reacitivity Human,Mouse,Rat,Monkey
Clone
Uniprot Q99714
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Formulation
Application WB,IHC-p,ELISA
Other Names 17 beta hydroxysteroid dehydrogenase 10,17 beta hydroxysteroid dehydrogenase type 10,17-beta-HSD 10,17-beta-hydroxysteroid dehydrogenase 10,17b HSD10,3 hydroxy 2 methylbutyryl CoA dehydrogenase,3 hydroxyacyl CoA dehydrogenase type 2,3 hydroxyacyl CoA dehydrogenase type II,3-hydroxy-2-methylbutyryl-CoA dehydrogenase,3-hydroxyacyl-CoA dehydrogenase type II,3-hydroxyacyl-CoA dehydrogenase type-2,AB binding alcohol dehydrogenase,ABAD,Ads9,Amyloid beta binding polypeptide,Amyloid beta peptide binding alcohol dehydrogenase,Amyloid beta peptide binding protein,Amyloid beta peptide binding protein,CAMR,DUPXp11.22,Endoplasmic Reticulum Amyloid Binding Protein,Endoplasmic reticulum associated amyloid beta peptide binding protein,Endoplasmic reticulum-associated amyloid beta-peptide-binding protein,ER associated amyloid beta-binding protein,ERAB,HADH 2,HADH2,HCD 2,HCD2,HCD2,Hsd17b10,Hydroxyacyl CoA Dehydrogenase type II,Hydroxyacyl Coenzyme A dehydrogenase type II,Hydroxysteroid (17 beta) dehydrogenase 10,Mental retardation X linked syndromic 11,MHBD,Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase,Mitochondrial ribonuclease P protein 2,Mitochondrial RNase P protein 2,MRPP2,MRX17,SCHAD,SDR5C1,Short chain dehydrogenase/reductase family 5C member 1,Short chain L 3 hydroxyacyl CoA dehydrogenase type 2,Short chain type dehydrogenase/reductase XH98G2,Short-chain type dehydrogenase/reductase XH98G2,Type 10 17b HSD,Type 10 17beta hydroxysteroid dehydrogenase,Type II HADH,XH98G2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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