Anti-Human/Mouse/Rat/Monkey EIF4E Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1 (By similarity). Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA03710
Size	100μl
Host Type	Rabbit
Immunogen	Synthesized peptide derived from human eIF4E around the non-phosphorylation site of Ser209.
Specificity
Isotype	IgG
Reacitivity	Human,Mouse,Rat,Monkey
Clone
Uniprot	P06730
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Formulation
Application	WB,IHC-p,ELISA
Other Names	AUTS19,CBP,eIF 4E,eIF 4F 25 kDa subunit,EIF 4F,eIF-4E,eIF-4F 25 kDa subunit,eIF4E,EIF4E1,EIF4EL1,EIF4F,Eukaryotic translation initiation factor 4 E,Eukaryotic translation initiation factor 4E,Eukaryotic translation initiation factor 4E like 1,IF4E,Messanger RNA Cap Binding Protein eIF 4E,MGC111573,mRNA cap binding protein,mRNA cap-binding protein
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse/Rat/Monkey EIF4E Polyclonal Antibody

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