Anti-Human/Mouse/Rat/Monkey CRK Polyclonal Antibody

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03116
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human Crk II around the non-phosphorylation site of Y221.
Specificity
Isotype IgG
Reacitivity Human,Mouse,Rat,Monkey
Clone
Uniprot P46108
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names Adapter molecule crk,Avian sarcoma virus CT10 (v crk) oncogene homolog,CRK,CRK isoform 2,CRK isoform II,CRK,CRKII,FLJ38130,OTTHUMP00000115366,OTTHUMP00000198330,p38,Proto oncogene C crk,Proto-oncogene C-crk,v crk avian sarcoma virus CT10 oncogene homolog,v crk sarcoma virus CT10 oncogene homolog,v crk sarcoma virus CT10 oncogene homolog (avian)
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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