Anti-Human/Mouse/Rat MAP2K5 Polyclonal Antibody

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04211
Size 100μl
Host Type Rabbit
Immunogen Recombinant Protein
Specificity Expressed in many adult tissues. Abundant in heart and skeletal muscle.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q13163
Concentration 1mg/mL
Dilution WB 1:1000-2000, IHC 1:200-500
Formulation
Application WB,IHC-p
Other Names Dual specificity mitogen activated protein kinase kinase 5,Dual specificity mitogen-activated protein kinase kinase 5,EC 2.7.12.2,HsT17454,MAP kinase kinase 5,MAP kinase kinase MEK5b,MAP2K5,MAPK/ERK kinase 5,MAPKK 5,MAPKK5,MEK 5,mitogen-activated protein kinase kinase 5,MKK5,MP2K5,PRKMK5,Protein kinase,mitogen-activated,kinase 5,SAPKK5,SKK5
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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