Anti-Human/Mouse/Rat MAG Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA02643
Size	100μl
Host Type	Rabbit
Immunogen	Synthesized peptide derived from the C-terminal region of human MAG.
Specificity	Both isoform 1 and isoform 2 are detected in myelinated structures in the central and peripheral nervous system, in periaxonal myelin and at Schmidt-Lanterman incisures (PubMed:9495552, PubMed:6200494). Detected in optic nerve, in oligodendroglia and in periaxonal myelin sheaths (PubMed:6200494). Detected in compact myelin (at protein level) (PubMed:6200494). Both isoform 1 and isoform 2 are detected in the central and peripheral nervous system (PubMed:9495552).
Isotype	IgG
Reacitivity	Human,Mouse,Rat
Clone
Uniprot	P20916
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, ELISA 1:20000
Formulation
Application	WB,ELISA
Other Names	GMA,MAG,MAG,Myelin associated glycoprotein,Myelin-associated glycoprotein,S MAG,S-MAG,Sialic acid binding Ig like lectin 4A,Sialic acid binding immunoglobulin like lectin 4A,Siglec 4a,Siglec-4a,SIGLEC4A,SPG75
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse/Rat MAG Polyclonal Antibody

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