Anti-Human/Mouse/Rat LRAT Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA04775
Size	100μl
Host Type	Rabbit
Immunogen	Synthesized peptide derived from the Internal region of human LRAT
Specificity	Hepatic stellate cells and endothelial cells (at protein level). Found at high levels in testis and liver, followed by retinal pigment epithelium, small intestine, prostate, pancreas and colon. Low expression observed in brain. In fetal tissues, expressed in retinal pigment epithelium and liver, and barely in the brain.
Isotype	IgG
Reacitivity	Human,Mouse,Rat
Clone
Uniprot	O95237
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Formulation
Application	WB,IHC-p,IF,ELISA
Other Names	LCA14,Lecithin retinol acyltransferase (phosphatidylcholine retinol O acyltransferase),Lecithin retinol acyltransferase,LRAT,LRAT,Phosphatidylcholine retinol O acyltransferase,Phosphatidylcholine--retinol O-acyltransferase
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse/Rat LRAT Polyclonal Antibody

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