Anti-Human/Mouse/Rat KRT14/17 Polyclonal Antibody

KRT14 (Keratin 14) is a Protein Coding gene. Diseases associated with KRT14 include Epidermolysis Bullosa Simplex, Koebner Type and Epidermolysis Bullosa Simplex, Recessive 1. Among its related pathways are Corticotropin-releasing hormone signaling pathway and Glucocorticoid receptor regulatory network. GO annotations related to this gene include structural molecule activity and keratin filament binding. An important paralog of this gene is KRT16. KRT17 (Keratin 17) is a Protein Coding gene. Diseases associated with KRT17 include Steatocystoma Multiplex and Pachyonychia Congenita 2. Among its related pathways are Glucocorticoid receptor regulatory network and Keratinization. GO annotations related to this gene include structural molecule activity and MHC class II receptor activity. An important paralog of this gene is KRT14.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04536
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide from human protein
Specificity Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen.1 Publication
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot
Concentration 1mg/mL
Dilution WB 1:500-2000, ELISA 1:10000-20000
Formulation
Application WB,IHC-p,ELISA
Other Names KRT14,KRT17
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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