Anti-Human/Mouse/Rat KL Polyclonal Antibody

This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA07308
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human KL
Specificity Present in cortical renal tubules (at protein level). Soluble peptide is present in serum and cerebrospinal fluid. Expressed in kidney, placenta, small intestine and prostate. Down-regulated in renal cell carcinomas, hepatocellular carcinomas, and in chronic renal failure kidney.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9UEF7
Concentration 0.2 mg/mL
Dilution WB 1:200-1000, ELISA 1:1000-2000
Formulation
Application WB,ELISA
Other Names Kl,KLOT,Klotho peptide
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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