Anti-Human/Mouse/Rat Kcnk3 Polyclonal Antibody

TASK channels are highly sensitive to external pH in the physiological range. TASK-1 is expressed in brain and in rat heart, with high levels of expression in the right atrium. TASK-2, mainly expressed in kidney, is localized in cortical distal tubules and collecting ducts, suggesting a role in renal K+ transport. TASK-3 from rat cerebellum shares 54% identity with TASK-1, but less than 30% identity with TASK-2 and other tandem pore K+ channels.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11235
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human KCNK3
Specificity Very strong expression in heart, also detected in kidney, brain, skin, testis, lung, skeletal muscle, small intestine and stomach. Not detected in liver, thymus or spleen.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O35111
Concentration 0.2 mg/mL
Dilution WB 1:500-1:2000, IHC 1:10-1:50
Formulation
Application WB,IHC,ELISA
Other Names TASK,Task-1,cTBAK-1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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