Anti-Human/Mouse/Rat KCNJ16 Polyclonal Antibody

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which tends to allow potassium to flow into rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may function in fluid and pH balance regulation. Alternatively spliced transcript variants have been found for this gene.KCNJ16 (Potassium Voltage-Gated Channel Subfamily J Member 16) is a Protein Coding gene. Diseases associated with KCNJ16 include Sesame Syndrome and Campomelic Dysplasia. Among its related pathways are Inwardly rectifying K+ channels and GABA receptor activation. GO annotations related to this gene include inward rectifier potassium channel activity. An important paralog of this gene is KCNJ2.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04674
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from mouse KIR5.1 around the non-phosphorylation site of S416.
Specificity Widely expressed, with highest levels in adult and fetal kidney (at protein level). In the kidney, expressed in the proximal and distal convoluted tubules, but not in glomeruli nor collecting ducts.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9NPI9
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names 6430410F18Rik,AI132396,BIR9,Inward rectifier K channel Kir5.1,Inward rectifier K(+) channel Kir5.1,Inward rectifier potassium channel 16,IRK16,IRKG,KCNJ16,MGC33717,Potassium channel inwardly rectifying subfamily J member 16,Potassium inwardly rectifying channel subfamily J member 16,RP23-218O16.1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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