Anti-Human/Mouse/Rat KCNB1 Polyclonal Antibody

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smootHuman, Mouseuscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05151
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human Kv2.1/KCNB1 Polyclonal
Specificity Expressed in neocortical pyramidal cells (PubMed:24477962). Expressed in pancreatic beta cells (at protein level) (PubMed:12403834, PubMed:14988243). Expressed in brain, heart, lung, liver, colon, kidney and adrenal gland (PubMed:19074135). Expressed in the cortex, amygdala, cerebellum, pons, thalamus, hypothalamus, hippocampus and substantia nigra (PubMed:19074135).
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q14721
Concentration 1mg/mL
Dilution WB 1:500-2000, ELISA 1:10000-20000
Formulation
Application WB,ELISA
Other Names Delayed rectifier potassium channel 1,Delayed rectifier potassium channel Kv2.1,DRK 1,DRK1,h DRK1 K(+) channel,h-DRK1,hDRK 1,hDRK1,KCB 1,KCB1,KCNB1,KCNB1,KV2.1,Potassium channel protein DRK1,Potassium voltage gated channel shab related subfamily member 1,Potassium voltage-gated channel subfamily B member 1,Voltage-gated potassium channel subunit Kv2.1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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