Anti-Human/Mouse/Rat JNK3 Polyclonal Antibody

Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. Required for stress-induced neuronal apoptosis and the pathogenesis of glutamate excitotoxicity.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04573
Size 100μl
Host Type Rabbit
Immunogen Recombinant Protein of JNK3
Specificity Specific to a subset of neurons in the nervous system. Present in the hippocampus and areas, cerebellum, striatum, brain stem, and weakly in the spinal cord. Very weak expression in testis and kidney.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P53779
Concentration 1mg/mL
Dilution IHC 1:50-300
Formulation
Application IHC-p
Other Names c Jun kinase 3,c-Jun N-terminal kinase 3,cJun N terminal kinase 3,FLJ12099,FLJ33785,JNK3 alpha protein kinase,JNK3,JNK3A,MAP kinase 10,MAP kinase,MAP kinase p49 3F12,MAPK 10,Mapk10,MGC50974,mitogen activated protein kinase 10,Mitogen-activated protein kinase 10,MK10,p493F12,p54bSAPK,PRKM10,protein kinase mitogen activated 10,SAPK1b,Stress activated protein kinase 1b,stress activated protein kinase beta,Stress activated protein kinase JNK3,Stress-activated protein kinase JNK3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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