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Anti-Human/Mouse/Rat JAK3 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04644
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human JAK3 around the non-phosphorylation site of Tyr785.
Specificity In NK cells and an NK-like cell line but not in resting T-cells or in other tissues. The S-form is more commonly seen in hematopoietic lines, whereas the B-form is detected in cells both of hematopoietic and epithelial origins.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P52333
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names EC 2.7.10.2,JAK 3,JAK L,JAK-3,Jak3,JAK3 HUMAN,JAK3,JAKL,Janus kinase 3 (a protein tyrosine kinase,leukocyte),Janus kinase 3,Janus Kinase3,L JAK,L-JAK,Leukocyte janus kinase,LJAK,Protein tyrosine kinase leukocyte,Tyrosine protein kinase JAK3,Tyrosine-protein kinase JAK3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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