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Anti-Human/Mouse/Rat ITGA7 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11093
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human ITGA7
Specificity Isoforms containing segment A are predominantly expressed in skeletal muscle. Isoforms containing segment B are abundantly expressed in skeletal muscle, moderately in cardiac muscle, small intestine, colon, ovary and prostate and weakly in lung and testes. Isoforms containing segment X2D are expressed at low levels in fetal and adult skeletal muscle and in cardiac muscle, but are not detected in myoblasts and myotubes. In muscle fibers isoforms containing segment A and B are expressed at myotendinous and neuromuscular junctions; isoforms containing segment C are expressed at neuromuscular junctions and at extrasynaptic sites. Isoforms containing segments X1 or X2 or, at low levels, X1X2 are expressed in fetal and adult skeletal muscle (myoblasts and myotubes) and cardiac muscle.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q13683
Concentration 0.2 mg/mL
Dilution IHC 1:10-1:50
Formulation
Application IHC,ELISA
Other Names alpha 7,FLJ25220,Integrin alpha 7,Integrin alpha 7 chain,Integrin alpha 7 heavy chain,Integrin alpha 7 light chain,Integrin alpha-7 70 kDa form,ITA7,ITGA 7,Itga7
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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