Anti-Human/Mouse/Rat IRAK1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Isoform 1 binds rapidly but is then degraded allowing isoform 2 to mediate a slower, more sustained response to the cytokine. Isoform 2 is inactive suggesting that the kinase activity of this enzyme is not required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1.

List Price: $398

Buy 5 for $378.1 each and save 5%
Buy 21 for $358.2 each and save 10%
Buy 31 for $338.3 each and save 15%
Buy 51 for

Properties

Data Sheet	Click for Datasheet
Catalog Number	PA04626
Size	100μl
Host Type	Rabbit
Immunogen	Synthesized peptide derived from human IRAK-1 around the non-phosphorylation site of Thr387.
Specificity	Isoform 1 and isoform 2 are ubiquitously expressed in all tissues examined, with isoform 1 being more strongly expressed than isoform 2.
Isotype	IgG
Reacitivity	Human,Mouse,Rat
Clone
Uniprot	P51617
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:5000
Formulation
Application	WB,IF,ELISA
Other Names	AA48924,Il1rak,Interleukin 1 receptor associated kinase 1,Interleukin-1 receptor-associated kinase 1,IRAK,IRAK-1,Irak1,IRAK1-S,IRAK1,mPLK,OTTHUMP00000026014,OTTHUMP00000026015,OTTHUMP00000026020,OTTHUMP00000180621,Pelle,Pelle homolog,Pelle-like protein kinase,Plpk
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

Catalog NO.:	PA04626	Quantity:
*Applicant Name:		Salutation:
*Email:		Phone:
*Country:		*Organization:
Remarks:

How to order

Anti-Human/Mouse/Rat IRAK1 Polyclonal Antibody

Properties

Featured Products

Support

Products

Contact

Follow