Anti-Human/Mouse/Rat IMPDH2 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA09787
Size	100μl
Host Type	Rabbit
Immunogen	Recombinant protein of human IMPDH2
Specificity	IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
Isotype	IgG
Reacitivity	Human,Mouse,Rat
Clone
Uniprot	P12268
Concentration	0.5 mg/mL
Dilution	WB 1:500-1:2000, IHC 1:50-1:200
Formulation
Application	WB,IHC,ELISA
Other Names	IMDH2,IMP (inosine monophosphate) dehydrogenase 2,IMP dehydrogenase 2,IMP oxireductase 2,IMPD 2,IMPD2,IMPDH 2,IMPDH II,IMPDH-II,Impdh2,Inosine 5' monophosphate dehydrogenase 2,Inosine 5' phosphate dehydrogenase 2,Inosine monophosphate dehydrogenase type II,Inosine-5''-monophosphate dehydrogenase 2
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse/Rat IMPDH2 Polyclonal Antibody

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