Anti-Human/Mouse/Rat IMPDH1 Polyclonal Antibody

The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10188
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human IMPDH1
Specificity IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P20839
Concentration 0.6 mg/mL
Dilution WB 1:500-1:2000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names IMDH1,IMP (inosine monophosphate) dehydrogenase 1,IMP dehydrogenase 1,IMPD 1,IMPD,IMPD1,IMPDH 1,IMPDH I,IMPDH-I,Impdh1,Inosine 5' monophosphate dehydrogenase 1,Inosine monophosphate dehydrogenase 1,Inosine-5''-monophosphate dehydrogenase 1,LCA11,RP10,sWSS2608
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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