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Anti-Human/Mouse/Rat IL36RN Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
IL36RN (Interleukin 36 Receptor Antagonist) is a Protein Coding gene. Diseases associated with IL36RN include Psoriasis 14, Pustular and Pustulosis Palmaris Et Plantaris. Among its related pathways are Toll-Like receptor Signaling Pathways. GO annotations related to this gene include cytokine activity and interleukin-1 receptor antagonist activity. An important paralog of this gene is IL1RN.The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04426
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human IL-1F5.
Specificity Predominantly expressed in keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Detected also in the spleen, brain leukocyte and macrophage cell types. Increased in lesional psoriasis skin.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9UBH0
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:10000
Formulation
Application WB,ELISA
Other Names AI413231,Family of interleukin 1 delta,FIL1,FIL1 delta,FIL1(DELTA),FIL1D,Fil1delta,I36RA,IL 1 delta,IL 1 related protein 3,IL 1F5 (IL 1HY1,FIL1 delta,IL 1RP3,IL 1L1,IL 1 delta),Il 1h3,IL 1HY1,IL 1L1,IL 1ra homolog,IL 1ra homolog,IL1F5 (Canonical product IL 1F5a),IL 1RP3,IL-1 delta,IL-1-related protein 3,IL-1F5,IL-1HY1,IL-1L1,IL-1ra homolog 1,IL-1RP3,IL1F5,IL1HY1,IL1L1,IL1RP3,IL36RA,IL36RN,Interleukin 1 delta,Interleukin 1 family member 5 (delta),Interleukin 1 family member 5,Interleukin 1 HY1,Interleukin 1 like protein 1,Interleukin 1 receptor antagonist homolog 1,Interleukin 36 receptor antagonist,Interleukin-1 delta,Interleukin-1 family member 5,Interleukin-1 HY1,Interleukin-1 receptor antagonist homolog 1,Interleukin-1-like protein 1,Interleukin-36 receptor antagonist protein,MGC29840,PSORP,RP23-176J12.6
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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