Anti-Human/Mouse/Rat HMGB1 Polyclonal Antibody

DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells
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Properties

Data Sheet Click for Datasheet
Catalog Number PA07870
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human HMGB1
Specificity Ubiquituous. Expressed in platelets (PubMed:11154118).
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P09429
Concentration 0.4 mg/mL
Dilution IHC 1:10-1:50
Formulation
Application IHC,ELISA
Other Names Amphoterin,Chromosomal protein,nonhistone,HMG1,DKFZp686A04236,High mobility group 1,High mobility group box 1,High mobility group protein 1,High mobility group protein B1,high-mobility group (nonhistone chromosomal) protein 1,HMG-1,HMG1,HMG3,HMGB 1,HMGB1,HMGB1,NONHISTONE CHROMOSOMAL PROTEIN HMG1,SBP 1,Sulfoglucuronyl carbohydrate binding protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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