Anti-Human/Mouse/Rat Histone H3.3 Polyclonal Antibody

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04420
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human Histone H3.3 around the non-phosphorylation site of Ser31.
Specificity
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P84243
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names H3 histone family 3A,H3 histone family 3B,H3 histone,family 3B (H3.3B),H3.3,H3.3A,H3.3B,H33,H3F3,H3F3A,H3f3b,Histone H3.3,Histone H3.3Q,Histone H3.A,Histone H3.B,MGC87782,MGC87783
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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