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Anti-Human/Mouse/Rat Histamine H3 Receptor Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smootHuman, Mouseuscles and innervates the blood vessels and the heart in cardiovascular system.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04389
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human Histamine H3 Receptor
Specificity Expressed predominantly in the CNS, with the greatest expression in the thalamus and caudate nucleus. The various isoforms are mainly coexpressed in brain, but their relative expression level varies in a region-specific manner. Isoform 3 and isoform 7 are highly expressed in the thalamus, caudate nucleus and cerebellum while isoform 5 and isoform 6 show a poor expression. Isoform 5 and isoform 6 show a high expression in the amygdala, substantia nigra, cerebral cortex and hypothalamus. Isoform 7 is not found in hypothalamus or substantia nigra.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9Y5N1
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names G protein coupled receptor 97,G-protein coupled receptor 97,GPCR 97,GPCR97,H3R,HH 3R,HH3 R,HH3R,Histamine H3 receptor,Histamine receptor H3,HRH 3,HRH3,HRH3,OTTHUMP00000031459
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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