Anti-Human/Mouse/Rat HDAC8 Polyclonal Antibody

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12288
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human HDAC8
Specificity Weakly expressed in most tissues. Expressed at higher level in heart, brain, kidney and pancreas and also in liver, lung, placenta, prostate and kidney.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9BY41
Concentration 0.7 mg/mL
Dilution WB 1:500-1:2000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names CDA07,CDLS5,HD 8,HD8,HDAC 8,Hdac8,HDAC8,HDACL 1,HDACL1,Histone deacetylase 8,Histone deacetylase like 1,MRXS6,RPD 3,RPD3,WTS
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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