Anti-Human/Mouse/Rat HDAC4 Polyclonal Antibody

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11137
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human HDAC4
Specificity Ubiquitous.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P56524
Concentration 0.2 mg/mL
Dilution IHC 1:10-1:50
Formulation
Application IHC,ELISA
Other Names AHO3,BDMR,EC 3.5.1.98,HA6116,HD 4,HD4,HDAC 4,HDAC A,HDAC4,HDAC4,HDACA,Histone deacetylase 4,Histone Deacetylase A,KIAA0288
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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