Anti-Human/Mouse/Rat HCRT Polyclonal Antibody

This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10326
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human HCRT
Specificity Abundantly expressed in subthalamic nucleus but undetectable in other brain regions tested (hypothalamus was not tested) and in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O43612
Concentration 0.1 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names HCRT,HCRT1,HCRT2,hypocretin (orexin) neuropeptide precursor,Hypocretin 1,Hypocretin 2,hypocretin,NRCLP1,Orexin,Orexin A,Orexin B,Orexin precursor,OX,PPORX,PPOX,PREPROOREXIN
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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